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By addition ofdifferent side chains at position 7 of -lactamring (altering spectrum of activity) and at position3 of dihydrothiazine ring (affecting pharmaco-kinetics), a large number of semisynthetic com-pounds have been produced

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Diagnosing spinal osteomyelitis: a comparison of boneand Ga-67 scintigraphy and magnetic resonance imaging. Below a CPP threshold of 70 mmHg, they founda progressive increase in the TCD pulsatility index [PI = (peak systolic velocity – end-diastolic velocity)/timed mean velocity] (r = –0.942, P < .0001).